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The antibody against GHRHR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GHRHR (NP_000814.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against GHRHR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GHRHR (NP_000814.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-01378A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GHRHR |
| Target Synonyms | GRFR; GHRFR; IGHD4; IGHD1B; GHRHR | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GHRHR (NP_000814.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFSTVK | Uniprot ID | Q02643 |
Uniprot Id
Q02643
Target Species
Human
Target Name
GHRHR
Target Full Name
Growth hormone-releasing hormone receptor
Target Function
Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
Target Involvement
Growth hormone deficiency, isolated, 1B (IGHD1B)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family
Target Tissue Specificity
Pituitary gland.
Target Synonyms
GRFR; GHRFR; IGHD4; IGHD1B; GHRHR
Target Background
This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.
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