Rabbit anti-Human GPM6A Polyclonal Antibody

The antibody against GPM6A was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human GPM6A (NP_005268.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-08936A

Number

Cat.No	ADA-08936A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	GPM6A
Target Synonyms	M6A; GPM6; GPM6A	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	U-87MG	Application	ELISA, WB, IHC-P

Cat.No

ADA-08936A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

GPM6A

Target Synonyms

M6A; GPM6; GPM6A

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

U-87MG

Application

ELISA, WB, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GPM6A (NP_005268.1).	Target Species	Human
Immunogen Sequence	MEENMEEGQTQKGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQTYFEMARTAGDTLDVFTMIDIFKYVIYGIAAAFFVYGILLM	Uniprot ID	P51674

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GPM6A (NP_005268.1).

Target Species

Human

Immunogen Sequence

MEENMEEGQTQKGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQTYFEMARTAGDTLDVFTMIDIFKYVIYGIAAAFFVYGILLM

Uniprot ID

P51674

Background Information

Uniprot Id

P51674
Target Species

Human
Target Name

GPM6A
Target Full Name

Neuronal membrane glycoprotein M6-a
Target Function

Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, growth cone. Cell projection, dendritic spine. Cell projection, filopodium. Cell projection, neuron projection.
Target Protein Families

Myelin proteolipid protein family
Target Synonyms

GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a
Target Background

Predicted to enable calcium channel activity. Involved in neuron migration and stem cell differentiation. Located in extracellular exosome.

Rabbit anti-Human GPM6A Polyclonal Antibody

Specifications

Immunogen Information

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