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The antibody against INHBB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 293-407 of human INHBB (NP_002184.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against INHBB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 293-407 of human INHBB (NP_002184.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-08967A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | INHBB |
| Target Synonyms | INHBB | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, MCF7, SW620, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 293-407 of human INHBB (NP_002184.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | GLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA | Uniprot ID | P09529? |
Uniprot Id
P09529
Target Species
Human
Target Name
INHBB
Target Full Name
Inhibin beta B chain
Target Function
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Target Subcellular Location
Secreted.
Target Protein Families
TGF-beta family
Target Research Area
Signal Transduction, Neuroscience
Target Synonyms
Activin beta B chain ; Activin beta-B chain; INHBB; INHBB_HUMAN; Inhibin beta 2; Inhibin beta B chain; Inhibin beta B subunit
Target Background
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Polymorphisms near this gene are associated with pre-eclampsia in female human patients.
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