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The antibody against KAT6B was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against KAT6B was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09660A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KAT6B |
| Target Synonyms | qkf; MORF; MOZ2; GTPTS; MYST4; ZC2HC6B; querkopf; KAT6B | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, 293T, OVCAR3 | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | DLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEV | Uniprot ID | Q8WYB5 |
Uniprot Id
Q8WYB5
Target Species
Human
Target Name
KAT6B
Target Full Name
Histone acetyltransferase KAT6B
Target Function
Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Target Involvement
Ohdo syndrome, SBBYS variant (SBBYSS); Genitopatellar syndrome (GTPTS)
Target Subcellular Location
Nucleus.
Target Protein Families
MYST (SAS/MOZ) family
Target Tissue Specificity
Ubiquitously expressed, with high levels in heart, pancreas, testis and ovary.
Target Synonyms
DKFZp313G1618; FLJ90335; Histone acetyltransferase MORF; Histone acetyltransferase MOZ2; Histone acetyltransferase MYST4; KAT 6B; KIAA0383; Monocytic leukemia zinc finger protein related factor; Monocytic leukemia zinc finger protein-related factor; MOZ 2; MOZ; MOZ related factor; MOZ YBF2/SAS3 SAS2 and TIP60 protein 4; MOZ2; MYST 4; MYST histone acetyltransferase (monocytic leukemia) 4; MYST protein 4; MYST-4; MYST4; MYST4_HUMAN; OTTHUMP00000019866; OTTHUMP00000019867; OTTHUMP00000019869; OTTHUMP00000019870; QKF; Querkopf; SAS2 and TIP60 protein 4; YBF2/SAS3
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