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The antibody against KIF20A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 591-890 of human KIF20A (NP_005724.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against KIF20A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 591-890 of human KIF20A (NP_005724.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10099A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KIF20A |
| Target Synonyms | RCM6; MKLP2; RAB6KIFL; KIF20A | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, A-549, Mouse brain, Mouse lung, Mouse spleen, Mouse testis, Rat spleen | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 591-890 of human KIF20A (NP_005724.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O95235 | Immunogen Sequence |
Uniprot Id
O95235
Target Species
Human
Target Name
KIF20A
Target Full Name
Kinesin-like protein KIF20A
Target Function
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
Target Subcellular Location
Golgi apparatus. Cytoplasm, cytoskeleton, spindle.
Target Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
Target Synonyms
AA415432; FLJ21151; GG10 2; GG10_2; KI20A_HUMAN; KIF20A; kinesin family member 20A; Kinesin like protein KIF20A; Kinesin-like protein 174; Kinesin-like protein KIF20A; mitotic kinesin like protein 2; Mitotic kinesin-like protein 2; MKlp2; OTTHUMP00000159481; RAB6 interacting; kinesin like (rabkinesin6); Rab6-interacting kinesin-like protein; RAB6-INTERACTING PROTEIN; KINESIN-LIKE; RAB6KIFL; Rabkinesin 6; Rabkinesin-6
Target Background
Enables protein kinase binding activity. Involved in microtubule bundle formation; midbody abscission; and regulation of cytokinesis. Located in several cellular components, including cleavage furrow; intercellular bridge; and midbody. Implicated in restrictive cardiomyopathy.
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