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The antibody against LARP6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human LARP6 (NP_060827.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against LARP6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human LARP6 (NP_060827.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-08756A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LARP6 |
| Target Synonyms | ACHN; LARP6 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat brain, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human LARP6 (NP_060827.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9BRS8 | Immunogen Sequence |
Uniprot Id
Q9BRS8
Target Species
Human
Target Name
LARP6
Target Full Name
La-related protein 6
Target Function
Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Target Tissue Specificity
Expressed in numerous tissues.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Acheron; Achn; FLJ11196; La ribonucleoprotein domain family member 6; La-related protein 6; LARP6; LARP6_HUMAN
Target Background
Enables RNA binding activity and myosin binding activity. Involved in positive regulation of collagen biosynthetic process; positive regulation of mRNA binding activity; and positive regulation of translation. Located in nucleus. Part of polysome.
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