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The antibody against LHB/CGB1 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 21-141of human LHB(NP_000885.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against LHB/CGB1 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 21-141of human LHB(NP_000885.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-08459A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LHB/CGB1 |
| Target Synonyms | LHB; CGB4; HH23; LSH-B; LSH-beta; lutropin subunit beta; Lutropin subunit beta | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T transfected with LHB/CGB1 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant Protein corresponding to a sequence within amino acids 21-141of human LHB(NP_000885.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | SREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPTMMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFL | Uniprot ID | P01229 |
Uniprot Id
P01229
Target Species
Human
Target Name
LHB
Target Full Name
Lutropin subunit beta
Target Function
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
Target Involvement
Hypogonadotropic hypogonadism 23 without anosmia (HH23)
Target Subcellular Location
Secreted.
Target Protein Families
Glycoprotein hormones subunit beta family
Target Tissue Specificity
Pituitary gland.
Target Synonyms
LHB; CGB4; HH23; LSH-B; LSH-beta; lutropin subunit beta; Lutropin subunit beta
Target Background
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
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