Rabbit anti-Human LHCGR Polyclonal Antibody

The antibody against LHCGR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human LHCGR (NP_000224.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-12318A

Number

Cat.No	ADA-12318A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	Lhcgr
Target Synonyms	HHG; LHR; LCGR; LGR2; ULG5; LHRHR; LSH-R; LH/CGR; LH/CG-R; LHCGR	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse brain, Mouse testis, Rat kidney, Rat ovary, Rat testis	Application	ELISA, WB, IF/ICC

Cat.No

ADA-12318A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

Lhcgr

Target Synonyms

HHG; LHR; LCGR; LGR2; ULG5; LHRHR; LSH-R; LH/CGR; LH/CG-R; LHCGR

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse brain, Mouse testis, Rat kidney, Rat ovary, Rat testis

Application

ELISA, WB, IF/ICC

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human LHCGR (NP_000224.2).	Target Species	Human
Immunogen Sequence	TSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENFSKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYD	Uniprot ID	P22888

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human LHCGR (NP_000224.2).

Target Species

Human

Immunogen Sequence

TSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENFSKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYD

Uniprot ID

P22888

Background Information

Uniprot Id

P22888
Target Species

Human
Target Name

LHCGR
Target Full Name

Lutropin-choriogonadotropic hormone receptor
Target Function

Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Target Involvement

Familial male precocious puberty (FMPP); Luteinizing hormone resistance (LHR)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 1 family, FSH/LSH/TSH subfamily
Target Tissue Specificity

Gonadal and thyroid cells.
Target Research Area

Cardiovascular, Neuroscience
Target Synonyms

Gonadotropin receptor; Gpcr19-rs1; GTHR-II; HHG; LCGR; LGR2; LH-R; LH/CG R; LH/CG-R; LH/CGR; LHCGR; LHR; LHRHR; LSH R; LSH-R; LSHR_HUMAN; Luteinizing hormone receptor; Luteinizing hormone/choriogonadotropin receptor; Lutropin choriogonadotropic hormone receptor ; Lutropin choriogonadotropic receptor ; Lutropin-choriogonadotropic hormone receptor; ULG5
Target Background

This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.

Rabbit anti-Human LHCGR Polyclonal Antibody

Specifications

Immunogen Information

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