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The antibody against LRIG1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_056356.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against LRIG1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_056356.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01399A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LRIG1 |
| Target Synonyms | LIG1; LIG-1; LRIG1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse brain, Mouse skin, Raji | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_056356.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96JA1 | Immunogen Sequence |
Uniprot Id
Q96JA1
Target Species
Human
Target Name
LRIG1
Target Full Name
Leucine-rich repeats and immunoglobulin-like domains protein 1
Target Function
Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Widely expressed.
Target Synonyms
Leucine rich repeat protein; Leucine rich repeat protein LRIG1; leucine rich repeats and immunoglobulin like domains 1; Leucine-rich repeats and immunoglobulin-like domains protein 1; leucine-rich repeats- and immunoglobulin-like domains-cotnaining protein 1; LIG 1; LIG-1; LIG1; Lrig1; LRIG1_HUMAN; Ortholog of mouse integral membrane glycoprotein LIG 1
Target Background
Predicted to act upstream of or within several processes, including innervation; otolith morphogenesis; and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space.
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