Rabbit anti-Human LRRC7 Polyclonal Antibody

The antibody against LRRC7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 730-890 of human LRRC7 (NP_065845.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-03440A

Number

Cat.No	ADA-03440A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	LRRC7
Target Synonyms	DENSIN; LRRC7	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, Mouse brain	Application	ELISA, WB, IF/ICC

Cat.No

ADA-03440A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

LRRC7

Target Synonyms

DENSIN; LRRC7

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, Mouse brain

Application

ELISA, WB, IF/ICC

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 730-890 of human LRRC7 (NP_065845.1).	Target Species	Human
Immunogen Sequence	FPQPLDSKPLLSQREAVPPGNIPQRPDRLPMSDTFTDNWTDGSHYDNTGFVAEETTAENANSNPLLSSKSRSTSSHGRRPLIRQDRIVGVPLELEQSTHRHTPETEVPPSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKEHIKESTEIPSPFSP	Uniprot ID	Q96NW7

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 730-890 of human LRRC7 (NP_065845.1).

Target Species

Human

Immunogen Sequence

FPQPLDSKPLLSQREAVPPGNIPQRPDRLPMSDTFTDNWTDGSHYDNTGFVAEETTAENANSNPLLSSKSRSTSSHGRRPLIRQDRIVGVPLELEQSTHRHTPETEVPPSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKEHIKESTEIPSPFSP

Uniprot ID

Q96NW7

Background Information

Uniprot Id

Q96NW7
Target Species

Human
Target Name

LRRC7
Target Full Name

Leucine-rich repeat-containing protein 7
Target Function

Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression.
Target Subcellular Location

Cytoplasm. Cell junction, synapse, postsynaptic density.
Target Protein Families

LAP (LRR and PDZ) protein family
Target Tissue Specificity

Brain-specific. Isoform 3 is ubiquitously expressed.
Target Synonyms

Densin 180; Densin; Densin-180; densin180; DKFZp686I1147; KIAA1365; Lamin associated polypeptide 1; LAP 1; Leucine rich repeat containing 7; Leucine rich repeat containing protein 7; Leucine-rich repeat-containing protein 7; Lrrc 7 ; LRRC7; LRRC7_HUMAN; MGC144918; OTTHUMP00000065336; OTTHUMP00000065337; OTTHUMP00000065338; Protein Lap 1; Protein lap1
Target Background

Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; positive regulation of neuron projection development; and receptor clustering. Located in several cellular components, including centrosome; cytosol; and nucleoplasm.

Rabbit anti-Human LRRC7 Polyclonal Antibody

Specifications

Immunogen Information

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