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Rabbit anti-Human MAFG Polyclonal Antibody

The antibody against MAFG was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-162 of human MAFG (NP_002350.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08819A

The antibody against MAFG was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-162 of human MAFG (NP_002350.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-08819A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMAFG
Target SynonymshMAF; MAFGFormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidneyApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-162 of human MAFG (NP_002350.1).Target SpeciesHuman
Immunogen SequenceMTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARSUniprot IDO15525
Background Information
  • Uniprot Id

    O15525

  • Target Species

    Human

  • Target Name

    MAFG

  • Target Full Name

    Transcription factor MafG

  • Target Function

    Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NFE2L2. Activates globin gene expression when associated with NFE2L2. May be involved in signal transduction of extracellular H(+)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family, Maf subfamily

  • Target Tissue Specificity

    Highly expressed in skeletal muscle. Also expressed in heart and brain.

  • Target Synonyms

    AA545192; Basic leucine zipper transcription factor MafG; C630022N07Rik; hMAF; MAFG; MAFG v maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian); MAFG_HUMAN; MGC13090; MGC20149 ; RP23 84C12.9; Transcription factor MafG; V maf musculoaponeurotic fibrosarcoma oncogene homolog G; V-maf musculoaponeurotic fibrosarcoma oncogene homolog G

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