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Rabbit anti-Human MAFK Polyclonal Antibody

The antibody against MAFK was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-50 of human MAFK (NP_002351.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10506A

The antibody against MAFK was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-50 of human MAFK (NP_002351.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-10506A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMAFK
Target SynonymsP18; NFE2U; MAFKFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesLO2, SGC-7901ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-50 of human MAFK (NP_002351.1).Target SpeciesHuman
Immunogen SequenceMTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTUniprot IDO60675
Background Information
  • Uniprot Id

    O60675

  • Target Species

    Human

  • Target Name

    MAFK

  • Target Full Name

    Transcription factor MafK

  • Target Function

    Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1/NRF1, NFE2L2/NRF2 and NFE2L3/NRF3, and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family, Maf subfamily

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    Erythroid transcription factor NF E2 p18 subunit ; Erythroid transcription factor NF-E2 p18 subunit; FLJ32205; MAFK; MAFK_HUMAN; MGC71717 ; Nfe2u; P18; Transcription factor MafK; V maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)

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