Rabbit anti-Human MARS Polyclonal Antibody

The antibody against MARS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MARS (NP_004981.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-08896A

Number

Cat.No	ADA-08896A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	MARS
Target Synonyms	MRS; ILLD; MARS; TTD9; CMT2U; ILFS2; METRS; MTRNS; SPG70	Form	Liquid
Species Reactivity	Human, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, HepG2, HT-1080, SGC-7901, SW480	Application	ELISA, WB, IHC-P

Cat.No

ADA-08896A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

MARS

Target Synonyms

MRS; ILLD; MARS; TTD9; CMT2U; ILFS2; METRS; MTRNS; SPG70

Form

Liquid

Species Reactivity

Human, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, HepG2, HT-1080, SGC-7901, SW480

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MARS (NP_004981.2).	Target Species	Human
Uniprot ID	P56192	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MARS (NP_004981.2).

Target Species

Human

Uniprot ID

P56192

Immunogen Sequence

Background Information

Uniprot Id

P56192
Target Species

Human
Target Name

MARS1
Target Full Name

Methionine--tRNA ligase, cytoplasmic
Target Function

Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus.
Target Involvement

Interstitial lung and liver disease (ILLD); Charcot-Marie-Tooth disease 2U (CMT2U)
Target Subcellular Location

Cytoplasm, cytosol. Nucleus, nucleolus.
Target Protein Families

Class-I aminoacyl-tRNA synthetase family
Target Synonyms

cytoplasmic; FLJ35667; Mars; Methionine tRNA ligase 1; Methionine tRNA ligase 1 cytoplasmic; Methionine tRNA ligase; Methionine tRNA synthetase ; Methionine--tRNA ligase; Methionyl tRNA synthetase cytoplasmic; Methionyl-tRNA synthetase; MetRS; MRS; MTRNS; SYMC_HUMAN
Target Background

This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules.

Rabbit anti-Human MARS Polyclonal Antibody

Specifications

Immunogen Information

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