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Rabbit anti-Human MFI2 Polyclonal Antibody

The antibody against MFI2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human MFI2 (NP_201573.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-02907A

The antibody against MFI2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human MFI2 (NP_201573.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-02907A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMFI2
Target SynonymsMTf; MFI2; MTF1; CD228; MAP97FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive Samples293T, A375, Mouse brain, Mouse liver, Mouse thymus, SW480ApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human MFI2 (NP_201573.1).Target SpeciesHuman
Immunogen SequenceGMEVRWCATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVTIDTLKGVKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSESLCRLCRGDSSGEGVCDUniprot IDP08582
Background Information
  • Uniprot Id

    P08582

  • Target Species

    Human

  • Target Name

    MELTF

  • Target Full Name

    Melanotransferrin

  • Target Function

    Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.

  • Target Subcellular Location

    [Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor.

  • Target Protein Families

    Transferrin family

  • Target Tissue Specificity

    Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts.

  • Target Research Area

    Others

  • Target Synonyms

    Antigen p97; CD228; CD228 antigen; MAP97 ; Melanoma associated antigen p97; Melanoma-associated antigen p97; Melanotransferrin; Mfi2; MTF1 ; TRFM_HUMAN

  • Target Background

    The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants.

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