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The antibody against MMP10 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 237-476 of human MMP10 (NP_002416.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against MMP10 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 237-476 of human MMP10 (NP_002416.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-12275A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MMP10 |
| Target Synonyms | SL-2; STMY2; MMP10 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | BT-474, M21, MCF7, U-251MG | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 237-476 of human MMP10 (NP_002416.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P09238 | Immunogen Sequence |
Uniprot Id
P09238
Target Species
Human
Target Name
MMP10
Target Full Name
Stromelysin-2
Target Function
Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Peptidase M10A family
Target Research Area
Developmental Biology
Target Synonyms
Matrix metallopeptidase 10 (stromelysin 2); Matrix metalloprotease 10; Matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase 10; Matrix metalloproteinase-10; MMP 10; MMP-10; Mmp10; MMP10_HUMAN; SL 2; SL-2; SL2; STMY 2; STMY2; Stromelysin 2; Stromelysin II; Stromelysin-2; Stromelysin2; StromelysinII; Transin 2; Transin-2; Transin2
Target Background
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11.
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