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The antibody against MORC3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 640-939 of human MORC3 (NP_056173.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MORC3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 640-939 of human MORC3 (NP_056173.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05082A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MORC3 |
| Target Synonyms | NXP2; ZCW5; ZCWCC3; MORC3 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 640-939 of human MORC3 (NP_056173.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q14149 | Immunogen Sequence |
Uniprot Id
Q14149
Target Species
Human
Target Name
MORC3
Target Full Name
MORC family CW-type zinc finger protein 3
Target Function
Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in vitro. May be required for influenza A transcription during viral infection. Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0.
Target Subcellular Location
Nucleus, nucleoplasm. Nucleus matrix. Nucleus, PML body.
Target Tissue Specificity
Expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney.
Target Research Area
Others
Target Synonyms
KIAA0136; Microrchidia 3; MORC family CW type zinc finger 3; MORC family CW type zinc finger protein 3; MORC family CW-type zinc finger protein 3; MORC3; MORC3_HUMAN; Nuclear matrix protein 2; Nuclear matrix protein NXP2; NXP2; ZCW5; ZCWCC3; Zinc finger CW type coiled coil domain 3; Zinc finger CW type coiled coil domain protein 3; Zinc finger CW type with coiled coil domain 3; Zinc finger CW-type coiled-coil domain protein 3
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