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The antibody against MRPS25 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 104-173 of human MRPS25 (NP_071942.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MRPS25 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 104-173 of human MRPS25 (NP_071942.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01052A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPS25 |
| Target Synonyms | RPMS25; COXPD50; MRP-S25; MRPS25 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A-549, BxPC-3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 104-173 of human MRPS25 (NP_071942.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | KILGKNEETLREEEEEKKQLSHPANFGPRKYCLRECICEVEGQVPCPSLVPLPKEMRGKYKAALKADAQD | Uniprot ID | P82663 |
Uniprot Id
P82663
Target Species
Human
Target Name
MRPS25
Target Full Name
Small ribosomal subunit protein mS25
Target Subcellular Location
Mitochondrion.
Target Protein Families
Mitochondrion-specific ribosomal protein mS25 family
Target Synonyms
MRPS25; RPMS25; 28S ribosomal protein S25; mitochondrial; MRP-S25; S25mt; Mitochondrial small ribosomal subunit protein mS25
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4. Alternative splicing results in multiple transcript variants.
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