Rabbit anti-Human MTTP Polyclonal Antibody

The antibody against MTTP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 19-160 of human MTTP (NP_000244.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05875A

Number

Cat.No	ADA-05875A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	MTTP
Target Synonyms	ABL; MTP; MTTP	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse small intestine, Rat small intestine	Application	ELISA, WB

Cat.No

ADA-05875A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

MTTP

Target Synonyms

ABL; MTP; MTTP

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse small intestine, Rat small intestine

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 19-160 of human MTTP (NP_000244.2).	Target Species	Human
Immunogen Sequence	VKGHTTGLSLNNDRLYKLTYSTEVLLDRGKGKLQDSVGYRISSNVDVALLWRNPDGDDDQLIQITMKDVNVENVNQQRGEKSIFKGKSPSKIMGKENLEALQRPTLLHLIHGKVKEFYSYQNEAVAIENIKRGLASLFQTQL	Uniprot ID	P55157

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 19-160 of human MTTP (NP_000244.2).

Target Species

Human

Immunogen Sequence

VKGHTTGLSLNNDRLYKLTYSTEVLLDRGKGKLQDSVGYRISSNVDVALLWRNPDGDDDQLIQITMKDVNVENVNQQRGEKSIFKGKSPSKIMGKENLEALQRPTLLHLIHGKVKEFYSYQNEAVAIENIKRGLASLFQTQL

Uniprot ID

P55157

Background Information

Uniprot Id

P55157
Target Species

Human
Target Name

MTTP
Target Full Name

Microsomal triglyceride transfer protein large subunit
Target Function

Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B. May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins.
Target Involvement

Abetalipoproteinemia (ABL)
Target Subcellular Location

Endoplasmic reticulum. Golgi apparatus.
Target Tissue Specificity

Liver and small intestine. Also found in ovary, testis and kidney.
Target Synonyms

ABL; Microsomal triglyceride transfer protein (large polypeptide 88kDa); Microsomal triglyceride transfer protein 88kD; Microsomal triglyceride transfer protein; Microsomal triglyceride transfer protein large subunit; MTP; MTP large subunit; MTP_HUMAN; MTTP; Transfer RNA, mitochondrial, proline; tRNA-Pro, mitochondrial
Target Background

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

Rabbit anti-Human MTTP Polyclonal Antibody

Specifications

Immunogen Information

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