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Rabbit anti-Human Mucin 5AC (MUC5AC) Polyclonal Antibody

The antibody against Mucin 5AC (MUC5AC) was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1550-1900 of human Mucin 5AC (MUC5AC) (NP_001291288.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09096A

The antibody against Mucin 5AC (MUC5AC) was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1550-1900 of human Mucin 5AC (MUC5AC) (NP_001291288.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09096A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMucin 5AC (MUC5AC)
Target SynonymsTBM; leB; MUC5; mucin; Mucin 5AC (MUC5AC)FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse stomachApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1550-1900 of human Mucin 5AC (MUC5AC) (NP_001291288.1).Target SpeciesHuman
Uniprot IDP98088Immunogen Sequence
Background Information
  • Uniprot Id

    P98088

  • Target Species

    Human

  • Target Name

    MUC5AC

  • Target Full Name

    Mucin-5AC

  • Target Function

    Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD).

  • Target Subcellular Location

    Secreted.

  • Target Tissue Specificity

    Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.

  • Target Synonyms

    TBM; leB; MUC5; mucin; Mucin 5AC (MUC5AC)

  • Target Background

    Predicted to be an extracellular matrix structural constituent. Involved in phosphatidylinositol-mediated signaling. Located in cytoplasm; extracellular space; and mucus layer. Implicated in dry eye syndrome. Biomarker of several diseases, including Sjogren's syndrome; biliary tract disease (multiple); cystic fibrosis; eye disease (multiple); and pancreatic cancer (multiple).

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