Rabbit anti-Human NPTN Polyclonal Antibody

The antibody against NPTN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 29-200 of human NPTN (NP_059429.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01839A

Number

Cat.No	ADA-01839A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	NPTN
Target Synonyms	GP55; GP65; SDR1; np55; np65; SDFR1; NPTN	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Jurkat, SKOV3	Application	ELISA, WB

Cat.No

ADA-01839A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

NPTN

Target Synonyms

GP55; GP65; SDR1; np55; np65; SDFR1; NPTN

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Jurkat, SKOV3

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 29-200 of human NPTN (NP_059429.1).	Target Species	Human
Immunogen Sequence	QNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC	Uniprot ID	Q9Y639

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 29-200 of human NPTN (NP_059429.1).

Target Species

Human

Immunogen Sequence

QNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC

Uniprot ID

Q9Y639

Background Information

Uniprot Id

Q9Y639
Target Species

Human
Target Name

NPTN
Target Full Name

Neuroplastin
Target Function

Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. Also acts as a chaperone for ATP2B1; stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane.
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell junction, synapse, postsynaptic density.
Target Tissue Specificity

Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level).
Target Synonyms

GP55; GP65; Neuroplastin; np55; np65; Nptn; NPTN_HUMAN; SDFR1; SDR-1; SDR1; stromal cell derived factor receptor 1; Stromal cell-derived receptor 1
Target Background

This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human NPTN Polyclonal Antibody

Specifications

Immunogen Information

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