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Rabbit anti-Human NTF4 Polyclonal Antibody

The antibody against NTF4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-210 of human NTF4 (NP_006170.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06498A

The antibody against NTF4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-210 of human NTF4 (NP_006170.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-06498A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNTF4
Target SynonymsNT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5; NTF4FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHT-1080ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 25-210 of human NTF4 (NP_006170.1).Target SpeciesHuman
Immunogen SequenceQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRAUniprot IDP34130
Background Information
  • Uniprot Id

    P34130

  • Target Species

    Human

  • Target Name

    NTF4

  • Target Full Name

    Neurotrophin-4

  • Target Function

    Target-derived survival factor for peripheral sensory sympathetic neurons.

  • Target Involvement

    Glaucoma 1, open angle, O (GLC1O)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    NGF-beta family

  • Target Tissue Specificity

    Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    GLC10; GLC1O; Neurotrophic factor 4; Neurotrophic factor 5; Neurotrophin 4; Neurotrophin 4/5; Neurotrophin 5 (neurotrophin 4/5); Neurotrophin 5; Neurotrophin-4; Neurotrophin-5; Neutrophic factor 4; Neutrophic factor 5; NT 4; NT 4/5; NT 5; NT-4; NT-5; NT4; NT4/5; NT4P; NT5; NTF4; NTF4_HUMAN; NTF5

  • Target Background

    This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.

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