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The antibody against OSGEPL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human OSGEPL1 (NP_071748.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against OSGEPL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human OSGEPL1 (NP_071748.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-01818A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OSGEPL1 |
| Target Synonyms | Qri7; OSGEPL; OSGEPL1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse kidney, Rat brain, Mouse liver, Mouse testis, Rat liver | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human OSGEPL1 (NP_071748.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H4B0 | Immunogen Sequence |
Uniprot Id
Q9H4B0
Target Species
Human
Target Name
OSGEPL1
Target Full Name
tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial
Target Function
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
Target Subcellular Location
Mitochondrion.
Target Protein Families
KAE1 / TsaD family
Target Tissue Specificity
Widely expressed, with maximum expression in pituitary gland, prostate, rectum and uterus.
Target Synonyms
O sialoglycoprotein endopeptidase like 1 ; O sialoglycoprotein endopeptidase like protein 1; osgepl1; OSGP2_HUMAN; Probable O sialoglycoprotein endopeptidase 2; Probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1; Putative sialoglycoprotease type 2; Qri7; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1
Target Background
Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Located in mitochondrion.
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