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Rabbit anti-Human PABPC5 Polyclonal Antibody

The antibody against PABPC5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-382 of human PABPC5 (NP_543022.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08884A

The antibody against PABPC5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-382 of human PABPC5 (NP_543022.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-08884A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePABPC5
Target SynonymsPABP5; PABPC5FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesA375, MCF7, Mouse liver, Mouse skeletal muscle, SH-SY5YApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-382 of human PABPC5 (NP_543022.1).Target SpeciesHuman
Uniprot IDQ96DU9Immunogen Sequence
Background Information
  • Uniprot Id

    Q96DU9

  • Target Species

    Human

  • Target Name

    PABPC5

  • Target Full Name

    Polyadenylate-binding protein 5

  • Target Function

    Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.

  • Target Subcellular Location

    Cytoplasm.; [Isoform 2]: Mitochondrion matrix. Note=Co-fractionates with mtDNA and co-immunoprecipitates with the mitochondrial poly(A) polymerase.

  • Target Tissue Specificity

    Expressed in fetal brain and in a range of adult tissues.

  • Target Synonyms

    PABPC5; PABP5; Polyadenylate-binding protein 5; PABP-5; Poly(A)-binding protein 5

  • Target Background

    This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder.

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