Rabbit anti-Human PARD6B Polyclonal Antibody

The antibody against PARD6B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 253-372 of human PARD6B (NP_115910.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03862A

Number

Cat.No	ADA-03862A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PARD6B
Target Synonyms	PAR6B; PARD6B	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HepG2, MCF7, SH-SY5Y	Application	ELISA, WB

Cat.No

ADA-03862A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PARD6B

Target Synonyms

PAR6B; PARD6B

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HepG2, MCF7, SH-SY5Y

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 253-372 of human PARD6B (NP_115910.1).	Target Species	Human
Immunogen Sequence	NNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQKLLEEDGTIITL	Uniprot ID	Q9BYG5

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 253-372 of human PARD6B (NP_115910.1).

Target Species

Human

Immunogen Sequence

NNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQKLLEEDGTIITL

Uniprot ID

Q9BYG5

Background Information

Uniprot Id

Q9BYG5
Target Species

Human
Target Name

PARD6B
Target Full Name

Partitioning defective 6 homolog beta
Target Function

Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Target Subcellular Location

Cytoplasm. Cell membrane. Cell junction, tight junction.
Target Protein Families

PAR6 family
Target Tissue Specificity

Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
Target Synonyms

PARD6B; PAR6BPartitioning defective 6 homolog beta; PAR-6 beta; PAR-6B
Target Background

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.

Rabbit anti-Human PARD6B Polyclonal Antibody

Specifications

Immunogen Information

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