Rabbit anti-Human PDE7A Polyclonal Antibody

The antibody against PDE7A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 345-456 of human PDE7A (NP_002594.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05286A

Number

Cat.No	ADA-05286A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PDE7A
Target Synonyms	HCP1; PDE7; PDE7A	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, Jurkat, Mouse testis, Rat testis	Application	ELISA, WB

Cat.No

ADA-05286A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PDE7A

Target Synonyms

HCP1; PDE7; PDE7A

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, Jurkat, Mouse testis, Rat testis

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 345-456 of human PDE7A (NP_002594.1).	Target Species	Human
Immunogen Sequence	ELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYLVEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSEDTDAAFELNSQLLPQENRLS	Uniprot ID	Q13946

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 345-456 of human PDE7A (NP_002594.1).

Target Species

Human

Immunogen Sequence

ELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYLVEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSEDTDAAFELNSQLLPQENRLS

Uniprot ID

Q13946

Background Information

Uniprot Id

Q13946
Target Species

Human
Target Name

PDE7A
Target Full Name

High affinity 3',5'-cyclic-AMP phosphodiesterase 7A
Target Function

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction.
Target Subcellular Location

[Isoform PDE7A1]: Cytoplasm, cytosol. Note=PDE7A1 (57 kDa) is located mostly to soluble cellular fractions.; [Isoform PDE7A2]: Cytoplasm. Note=PDE7A2 (50 kDa) is located to particulate cellular fractions.
Target Protein Families

Cyclic nucleotide phosphodiesterase family, PDE7 subfamily
Target Tissue Specificity

PDE7A1 is found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. PDE7A2 is found abundantly in skeletal muscle and at low levels in heart.
Target Synonyms

5''-cyclic phosphodiesterase 7A; HCP 1; HCP1; High affinity cAMP specific 3'5' cyclic phosphodiesterase 7A; High affinity cAMP-specific 3''; P2A; PDE 7; PDE 7A; PDE1/PDE2 yeast human complement of; PDE7; PDE71; PDE7A; PDE7A_HUMAN; Phosphodiesterase 7A; Phosphodiesterase isozyme 7; Phosphodiesterase7A; Rolipram insensitive phosphodiesterase type 7 ; TM 22; TM22

Rabbit anti-Human PDE7A Polyclonal Antibody

Specifications

Immunogen Information

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