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The antibody against PFN4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human PFN4 (NP_955378.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PFN4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human PFN4 (NP_955378.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06108A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PFN4 |
| Target Synonyms | PFN4 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Rat heart | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human PFN4 (NP_955378.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MSHLQSLLLDTLLGTKHVDSAALIKIQERSLCVASPGFNVTPSDVRTLVNGFAKNPLQARREGLYFKGKDYRCVRADEYSLYAKNENTGVVVVKTHLYLLVATYTEGMYPSICVEATESLGDYLRKKGS | Uniprot ID | Q8NHR9 |
Uniprot Id
Q8NHR9
Target Species
Human
Target Name
PFN4
Target Full Name
Profilin-4
Target Function
Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Does not bind to actin, contrary to other family members.
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Protein Families
Profilin family
Target Tissue Specificity
Detected in testis (at protein level).
Target Synonyms
PFN4; Profilin-4; Profilin IV
Target Background
Predicted to enable actin monomer binding activity. Predicted to be involved in sequestering of actin monomers. Predicted to be located in cytoskeleton. Predicted to be active in cell cortex.
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