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The antibody against PLB1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1110-1415 of human PLB1 (NP_694566.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PLB1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1110-1415 of human PLB1 (NP_694566.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06436A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLB1 |
| Target Synonyms | PLB; PLB/LIP; PLB1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-431, HL-60, HT-29, Mouse lung, Mouse skeletal muscle, Mouse testis, Rat testis, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1110-1415 of human PLB1 (NP_694566.4). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6P1J6 | Immunogen Sequence |
Uniprot Id
Q6P1J6
Target Species
Human
Target Name
PLB1
Target Full Name
Phospholipase B1, membrane-associated
Target Function
Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity). Has dual phospholipase and lysophospholipase activities toward diacylphospholipids. Preferentially cleaves sn-2 ester bonds over sn-1 bonds. Acts as a lipase toward glycerolipid substrates. Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity. May also hydrolyze long chain retinyl esters such as retinyl palmitate. May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border
Target Subcellular Location
Apical cell membrane; Single-pass type I membrane protein.
Target Protein Families
'GDSL' lipolytic enzyme family, Phospholipase B1 subfamily
Target Tissue Specificity
Expressed in the epidermis (at protein level).
Target Synonyms
PLB1; PLB; Phospholipase B1; membrane-associated; Phospholipase B; hPLB; Phospholipase B/lipase; PLB/LIP) [Includes: Phospholipase A2; EC 3.1.1.4); Lysophospholipase; EC 3.1.1.5)]
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