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The antibody against PLCB2 was raised in rabbit using the Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 protein (1031-1185aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against PLCB2 was raised in rabbit using the Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 protein (1031-1185aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-54971A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLCB2 |
| Target Synonyms | 1 phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-2) (Phospholipase C-beta-2) (PLC-beta-2), PLCB2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 protein (1031-1185aa) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q00722 |
Uniprot Id
Q00722
Target Species
Human
Target Name
PLCB2
Target Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
Target Function
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Target Synonyms
PLC-beta-2; PLCB2
Target Background
The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to the second messengers inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
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