Rabbit anti-Human PLXNA4 Polyclonal Antibody

The antibody against PLXNA4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 24-220 of human PLXNA4 (NP_861440.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08885A

Number

Cat.No	ADA-08885A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PLXNA4
Target Synonyms	PLEXA4; PLXNA4A; PLXNA4B; FAYV2820; PRO34003; PLXNA4	Form	Liquid
Species Reactivity	Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat lung	Application	ELISA, WB

Cat.No

ADA-08885A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PLXNA4

Target Synonyms

PLEXA4; PLXNA4A; PLXNA4B; FAYV2820; PRO34003; PLXNA4

Form

Liquid

Species Reactivity

Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat lung

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 24-220 of human PLXNA4 (NP_861440.2).	Target Species	Human
Immunogen Sequence	TLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHD	Uniprot ID	Q9HCM2

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 24-220 of human PLXNA4 (NP_861440.2).

Target Species

Human

Immunogen Sequence

TLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHD

Uniprot ID

Q9HCM2

Background Information

Uniprot Id

Q9HCM2
Target Species

Human
Target Name

PLXNA4
Target Full Name

Plexin-A4
Target Function

Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein.
Target Protein Families

Plexin family
Target Synonyms

FAYV2820; KIAA1550; PLEXA4; Plexin-A4; PlexinA4; PLXA4_HUMAN; plxna4; PLXNA4A; PLXNA4B; PRO34003; UNQ2820/PRO34003
Target Background

Predicted to enable semaphorin receptor activity. Predicted to be involved in several processes, including axon guidance; positive regulation of axonogenesis; and regulation of GTPase activity. Predicted to act upstream of or within several processes, including nervous system development; regulation of axon extension involved in axon guidance; and regulation of negative chemotaxis. Predicted to be located in plasma membrane. Predicted to be part of semaphorin receptor complex. Predicted to be integral component of plasma membrane.

Rabbit anti-Human PLXNA4 Polyclonal Antibody

Specifications

Immunogen Information

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