Rabbit anti-Human PMCH Polyclonal Antibody

The antibody against PMCH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-165 of human PMCH (NP_002665.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02888A

Number

Cat.No	ADA-02888A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PMCH
Target Synonyms	MCH; ppMCH; PMCH	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HT-29, MCF7, Mouse liver	Application	ELISA, WB

Cat.No

ADA-02888A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PMCH

Target Synonyms

MCH; ppMCH; PMCH

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HT-29, MCF7, Mouse liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 22-165 of human PMCH (NP_002665.2).	Target Species	Human
Immunogen Sequence	ILLSASKSIRNLDDDMVFNTFRLGKGFQKEDTAEKSVIAPSLEQYKNDESSFMNEEENKVSKNTGSKHNFLNHGLPLNLAIKPYLALKGSVAFPAENGVQNTESTQEKREIGDEENSAKFPIGRRDFDMLRCMLGRVYRPCWQV	Uniprot ID	P20382

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 22-165 of human PMCH (NP_002665.2).

Target Species

Human

Immunogen Sequence

ILLSASKSIRNLDDDMVFNTFRLGKGFQKEDTAEKSVIAPSLEQYKNDESSFMNEEENKVSKNTGSKHNFLNHGLPLNLAIKPYLALKGSVAFPAENGVQNTESTQEKREIGDEENSAKFPIGRRDFDMLRCMLGRVYRPCWQV

Uniprot ID

P20382

Background Information

Uniprot Id

P20382
Target Species

Human
Target Name

PMCH
Target Full Name

Pro-MCH
Target Function

MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation.
Target Subcellular Location

Secreted.
Target Protein Families

Melanin-concentrating hormone family
Target Tissue Specificity

Predominantly expressed in lateral hypothalamus, also detected in pallidum, neocortex and cerebellum. Also found in thymus, brown adipose tissue, duodenum and testis (spermatogonia, early spermatocytes and Sertoli cells). No expression in peripheral blood
Target Synonyms

PMCH; MCHPro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid; NGE; Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine; NEI; Neuropeptide E-I); Melanin-concentrating hormone; MCH)]
Target Background

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include melanin-concentrating hormone (MCH), neuropeptide-glutamic acid-isoleucine (NEI), and neuropeptide-glycine-glutamic acid (NGE). Melanin-concentrating hormone is a 19-amino acid neuropeptide that stimulates hunger and may additionally regulate energy homeostasis, reproductive function, and sleep. Pseudogenes of this gene have been identified on chromosome 5.

Rabbit anti-Human PMCH Polyclonal Antibody

Specifications

Immunogen Information

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