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The antibody against POLE2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human POLE2 (NP_002683.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against POLE2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human POLE2 (NP_002683.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03277A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | POLE2 |
| Target Synonyms | DPE2; POLE2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human POLE2 (NP_002683.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P56282 | Immunogen Sequence |
Uniprot Id
P56282
Target Species
Human
Target Name
POLE2
Target Full Name
DNA polymerase epsilon subunit 2
Target Function
Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication.
Target Subcellular Location
Nucleus.
Target Protein Families
DNA polymerase epsilon subunit B family
Target Synonyms
DNA polymerase epsilon subunit 2; DNA polymerase epsilon subunit B; DNA polymerase II subunit 2; DPE 2; DPE2; DPOE2_HUMAN; POLE 2; POLE2; Polymerase (DNA directed) epsilon 2 (p59 subunit); Polymerase (DNA directed) epsilon 2; polymerase (DNA directed); epsilon 2; accessory subunit; Polymerase; DNA; epsilon-2
Target Background
DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.
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