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The antibody against PPT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 28-302 of human PPT2 (NP_005146.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PPT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 28-302 of human PPT2 (NP_005146.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09272A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPT2 |
| Target Synonyms | G14; PPT-2; C6orf8; PPT2 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 28-302 of human PPT2 (NP_005146.4). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UMR5 | Immunogen Sequence |
Uniprot Id
Q9UMR5
Target Species
Human
Target Name
PPT2
Target Full Name
Lysosomal thioesterase PPT2
Target Function
Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins.
Target Subcellular Location
Lysosome.
Target Protein Families
Palmitoyl-protein thioesterase family
Target Tissue Specificity
Broadly expressed, with highest levels in skeletal muscle.
Target Synonyms
PPT2Lysosomal thioesterase PPT2; PPT-2; EC 3.1.2.-; S-thioesterase G14
Target Background
This gene encodes a member of the palmitoyl-protein thioesterase family. The encoded glycosylated lysosomal protein has palmitoyl-CoA hydrolase activity in vitro, but does not hydrolyze palmitate from cysteine residues in proteins. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream EGFL8 (EGF-like-domain, multiple 8) gene.
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