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The antibody against PRRG2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human PRRG2 (NP_001303264.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PRRG2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human PRRG2 (NP_001303264.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05679A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PRRG2 |
| Target Synonyms | PRGP2; PRRG2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver, Mouse lung, Rat liver, Rat lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human PRRG2 (NP_001303264.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MSLGPEVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRGRVDVASLAVGLTGGILLIVLAGLGAFWYLRWRQHRGQQPCPQEAGLISPLSPLNPLGPPTPLPPPPPPPPGLPTYEQALAASGVHDAPPPPYTSLRRPH | Uniprot ID | O14669 |
Uniprot Id
O14669
Target Species
Human
Target Name
PRRG2
Target Full Name
Transmembrane gamma-carboxyglutamic acid protein 2
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Widely expressed with highest levels in kidney. Also highly expressed in the thyroid.
Target Synonyms
PRRG2; PRGP2; TMG2; Transmembrane gamma-carboxyglutamic acid protein 2; Proline-rich gamma-carboxyglutamic acid protein 2; Proline-rich Gla protein 2
Target Background
The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene.
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