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Rabbit anti-Human PRSS21 Polyclonal Antibody

The antibody against PRSS21 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-220 of human PRSS21 (NP_006790.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04639A

The antibody against PRSS21 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-220 of human PRSS21 (NP_006790.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04639A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePRSS21
Target SynonymsESP1; ESP-1; TEST1; TESTISIN; PRSS21FormLiquid
Species ReactivityMouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse testis, Rat testisApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 150-220 of human PRSS21 (NP_006790.1).Target SpeciesHuman
Immunogen SequenceTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDUniprot IDQ9Y6M0
Background Information
  • Uniprot Id

    Q9Y6M0

  • Target Species

    Human

  • Target Name

    PRSS21

  • Target Full Name

    Testisin

  • Target Function

    Could regulate proteolytic events associated with testicular germ cell maturation.

  • Target Subcellular Location

    Cell membrane; Lipid-anchor, GPI-anchor.

  • Target Protein Families

    Peptidase S1 family

  • Target Tissue Specificity

    Expressed predominantly in premeiotic testicular germ cells, mostly late pachytene and diplotene spermatocytes.

  • Target Research Area

    Cancer

  • Target Synonyms

    Eosinophil serine protease 1; ESP-1; ESP1 ; Prss21; Serine protease 21; TEST_HUMAN; TEST1; Testisin

  • Target Background

    This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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