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The antibody against PSAT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-370 of human PSAT1 (NP_478059.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PSAT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-370 of human PSAT1 (NP_478059.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10234A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PSAT1 |
| Target Synonyms | PSA; EPIP; NLS2; PSAT; PSATD; PSAT1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat brain, Mouse brain, Rat kidney, SKOV3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-370 of human PSAT1 (NP_478059.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y617 | Immunogen Sequence |
Uniprot Id
Q9Y617
Target Species
Human
Target Name
PSAT1
Target Full Name
Phosphoserine aminotransferase
Target Function
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Target Involvement
Phosphoserine aminotransferase deficiency (PSATD); Neu-Laxova syndrome 2 (NLS2)
Target Protein Families
Class-V pyridoxal-phosphate-dependent aminotransferase family, SerC subfamily
Target Tissue Specificity
Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
Target Synonyms
PSA; EPIP; NLS2; PSAT; PSATD; PSAT1
Target Background
This gene encodes a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, and 8.
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