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The antibody against PTPIP51/RMDN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 171-470 of human PTPIP51/RMDN3 (NP_060615.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against PTPIP51/RMDN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 171-470 of human PTPIP51/RMDN3 (NP_060615.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-11623A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PTPIP51/RMDN3 |
| Target Synonyms | RMD3; RMD-3; FAM82C; FAM82A2; ptpip51; PTPIP51/RMDN3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse kidney, 293T, HepG2, MCF7, Mouse brain, Mouse liver | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 171-470 of human PTPIP51/RMDN3 (NP_060615.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96TC7 | Immunogen Sequence |
Uniprot Id
Q96TC7
Target Species
Human
Target Name
RMDN3
Target Full Name
Regulator of microtubule dynamics protein 3
Target Function
Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.
Target Subcellular Location
Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
Target Protein Families
RMDN family
Target Tissue Specificity
Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high
Target Research Area
Apoptosis
Target Synonyms
RMDN3; FAM82A2; FAM82C; PTPIP51; hucep-10; UNQ3122/PRO10274; Regulator of microtubule dynamics protein 3; RMD-3; hRMD-3; Cerebral protein 10; Protein FAM82A2; Protein FAM82C; Protein tyrosine phosphatase-interacting protein 51; TCPTP-interacting protein 51
Target Background
Enables microtubule binding activity. Involved in cellular calcium ion homeostasis. Located in several cellular components, including intercellular bridge; mitochondrial outer membrane; and spindle.
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