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The antibody against RAB27B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human RAB27B (NP_004154.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RAB27B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human RAB27B (NP_004154.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11719A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RAB27B |
| Target Synonyms | C25KG; RAB27B | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, Mouse stomach, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human RAB27B (NP_004154.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O00194 | Immunogen Sequence |
Uniprot Id
O00194
Target Species
Human
Target Name
RAB27B
Target Full Name
Ras-related protein Rab-27B
Target Function
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes.
Target Subcellular Location
Membrane; Lipid-anchor. Late endosome.
Target Protein Families
Small GTPase superfamily, Rab family
Target Tissue Specificity
Expressed primarily in testis.
Target Research Area
Signal Transduction
Target Synonyms
C25KG; Rab27b; RAB27B member RAS oncogene family; RAS associated protein RAB27B; Ras related protein Rab 27b; Ras related protein Rab27b; Ras-related protein Rab-27B; RB27B_HUMAN; Small GTP binding protein rab27b
Target Background
Enables guanyl ribonucleotide binding activity; myosin V binding activity; and protein domain specific binding activity. Involved in multivesicular body sorting pathway and positive regulation of exocytosis. Located in Golgi stack and cytoplasmic vesicle.
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