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Rabbit anti-Human RBBP9 Polyclonal Antibody

The antibody against RBBP9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human RBBP9 (NP_006597.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-03951A

The antibody against RBBP9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human RBBP9 (NP_006597.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-03951A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRBBP9
Target SynonymsBOG; RBBP10; RBBP9FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, A375, LO2, U-87MGApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human RBBP9 (NP_006597.2).Target SpeciesHuman
Immunogen SequenceMASPSKAVIVPGNGGGDVTTHGWYGWVKKELEKIPGFQCLAKNMPDPITARESIWLPFMETELHCDEKTIIIGHSSGAIAAMRYAETHRVYAIVLVSAYTSDLGDENERASGYFTRPWQWEKIKANCPYIVQFGSTDDPFLPWKEQQEVADRLETKLHKFTDCGHFQNTEFHELITVVKSLLKVPAUniprot IDO75884
Background Information
  • Uniprot Id

    O75884

  • Target Species

    Human

  • Target Name

    RBBP9

  • Target Full Name

    Serine hydrolase RBBP9

  • Target Function

    Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1.

  • Target Protein Families

    RBBP9 family

  • Target Tissue Specificity

    Expressed at higher levels in tumor tissues such as carcinoma.

  • Target Synonyms

    B5T overexpressed gene protein; B5T-overexpressed gene protein; BOG; Bog protein ; MGC9236; OTTHUMP00000030360; Protein BOG; Putative hydrolase RBBP9; RBBP 10; RBBP 9; RBBP-10; RBBP-9; RBBP10; RBBP9; RBBP9_HUMAN; Retinoblastoma binding protein 10; Retinoblastoma binding protein 9; Retinoblastoma-binding protein 10; Retinoblastoma-binding protein 9; Retinoma binding protein 9

  • Target Background

    The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate.

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