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Rabbit anti-Human RGS7 Polyclonal Antibody

The antibody against RGS7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RGS7 (NP_002915.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02875A

The antibody against RGS7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RGS7 (NP_002915.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-02875A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRGS7
Target SynonymsRGS7FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RGS7 (NP_002915.3).Target SpeciesHuman
Uniprot IDP49802Immunogen Sequence
Background Information
  • Uniprot Id

    P49802

  • Target Species

    Human

  • Target Name

    RGS7

  • Target Full Name

    Regulator of G-protein signaling 7

  • Target Function

    Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS7/GNB5 dimer enhances GNAO1 GTPase activity. May play a role in synaptic vesicle exocytosis. Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling.

  • Target Subcellular Location

    Cytoplasm, cytosol. Cytoplasm. Cell membrane. Membrane; Peripheral membrane protein; Cytoplasmic side.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    RGS7; Regulator of G-protein signaling 7; RGS7

  • Target Background

    Enables G-protein beta-subunit binding activity and GTPase activator activity. Involved in positive regulation of GTPase activity. Located in cytosol.

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