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The antibody against RHBDL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 12-130 of human RHBDL2 (NP_060291.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RHBDL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 12-130 of human RHBDL2 (NP_060291.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05660A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RHBDL2 |
| Target Synonyms | RRP2; RHBDL2 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse stomach, Rat uterus | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 12-130 of human RHBDL2 (NP_060291.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MNLNMGREMKEELEEEEKMREDGGGKDRAKSKKVHRIVSKWMLPEKSRGTYLERANCFPPPVFIISISLAELAVFIYYAVWKPQKQWITLDTGILESPFIYSPEKREEAWRFISYMLVH | Uniprot ID | Q9NX52 |
Uniprot Id
Q9NX52
Target Species
Human
Target Name
RHBDL2
Target Full Name
Rhomboid-related protein 2
Target Function
Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3.
Target Subcellular Location
[Rhomboid-related protein 2, C-terminal fragment]: Cell membrane; Multi-pass membrane protein.
Target Protein Families
Peptidase S54 family
Target Research Area
Others
Target Synonyms
RHBDL2; Rhomboid-related protein 2; RRP2; EC 3.4.21.105; Rhomboid-like protein 2) [Cleaved into: Rhomboid-related protein 2; N-terminal fragment; NTF); Rhomboid-related protein 2; C-terminal fragment; CTF)]
Target Background
The protein encoded by this gene is a member of the rhomboid family of integral membrane proteins. This family contains proteins that are related to Drosophila rhomboid protein. Members of this family are found in both prokaryotes and eukaryotes and are thought to function as intramembrane serine proteases. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3. Two transcript variants encoding different isoforms have been found for this gene.
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