Rabbit anti-Human RPS24 Polyclonal Antibody

Uniprot Id

P62847

Target Species

Human

Target Name

RPS24

Target Full Name

Small ribosomal subunit protein eS24

Target Function

Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

Target Involvement

Diamond-Blackfan anemia 3 (DBA3)

Target Protein Families

Eukaryotic ribosomal protein eS24 family

Target Tissue Specificity

Mature tissues, such as adult brain, skeletal muscle, heart, and kidney, express low levels, whereas tissues and organs with significant populations of proliferating cells, such as fetal brain, placenta, bone marrow, and various glandular organs, contain

Target Research Area

Epigenetics and Nuclear Signaling

Target Synonyms

RPS2440S ribosomal protein S24; Small ribosomal subunit protein eS24

Target Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S24E family of ribosomal proteins. It is located in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Mutations in this gene result in Diamond-Blackfan anemia.