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The antibody against SEMA3B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 569-748 of human SEMA3B (NP_001005914.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SEMA3B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 569-748 of human SEMA3B (NP_001005914.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09392A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SEMA3B |
| Target Synonyms | SemA; SEMA5; SEMAA; semaV; LUCA-1; SEMA3B | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, Mouse kidney, A-549 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 569-748 of human SEMA3B (NP_001005914.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | SSRPALLEHKVFGVEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGVYLCAAVEQGFTQPLRRLSLHVLSATQAERLARAEEAAPAAPPGPKLWYRDFLQLVEPGGGGSANSLRMCRPQPALQSLPLESRRKGRNRRTHAPEPRAERGPRSATHW | Uniprot ID | Q13214 |
Uniprot Id
Q13214
Target Species
Human
Target Name
SEMA3B
Target Full Name
Semaphorin-3B
Target Function
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Target Subcellular Location
Secreted. Endoplasmic reticulum. Note=Accumulates in the endoplasmic reticulum.
Target Protein Families
Semaphorin family
Target Tissue Specificity
Expressed abundantly but differentially in a variety of neural and nonneural tissues.
Target Research Area
Cancer
Target Synonyms
SEM3B_HUMAN; Sema A(V); Sema V; Sema3b; Semaphorin V; Semaphorin-3B; Semaphorin-V
Target Background
The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants.
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