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The antibody against SERPINA6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 136-405 of human SERPINA6 (NP_001747.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SERPINA6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 136-405 of human SERPINA6 (NP_001747.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06155A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SERPINA6 |
| Target Synonyms | CBG; SERPINA6 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, A-431, HepG2, HL-60, HT-29, NCI-H460 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 136-405 of human SERPINA6 (NP_001747.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P08185 | Immunogen Sequence |
Uniprot Id
P08185
Target Species
Human
Target Name
SERPINA6
Target Full Name
Corticosteroid-binding globulin
Target Function
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
Target Involvement
Corticosteroid-binding globulin deficiency (CBG deficiency)
Target Subcellular Location
Secreted.
Target Protein Families
Serpin family
Target Tissue Specificity
Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells.
Target Research Area
Transport
Target Synonyms
CBG; CBG_HUMAN; corticosteroid binding globulin; Corticosteroid-binding globulin; serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6; Serpin A6; serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6; Serpina6; Transcortin
Target Background
This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.
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