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The antibody against SERPINE2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-398 of human SERPINE2 (NP_006207.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SERPINE2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-398 of human SERPINE2 (NP_006207.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10203A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SERPINE2 |
| Target Synonyms | GDN; PI7; PN1; PNI; PI-7; PN-1; GDNPF; SERPINE2 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 27-398 of human SERPINE2 (NP_006207.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P07093 | Immunogen Sequence |
Uniprot Id
P07093
Target Species
Human
Target Name
SERPINE2
Target Full Name
Glia-derived nexin
Target Function
Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Target Subcellular Location
Secreted, extracellular space.
Target Protein Families
Serpin family
Target Research Area
Cardiovascular
Target Synonyms
GDN; GDN_HUMAN; GDNPF; Glia derived nexin; Glia-derived nexin; Glial derived neurite promoting factor; P17; Peptidase inhibitor 7; Pi-7; Plasminogen activator inhibitor type 1; member 2; PN-1; PN1; PNI; Protease inhibitor 7; Protease nexin 1; Protease nexin I; Serpin E2; Serpin family E member 2; Serpin peptidase inhibitor; clade E (nexin; plasminogen activator inhibitor type 1); member 2; SERPINE 2 ; Serpine2
Target Background
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
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