Rabbit anti-Human SFRP2 Polyclonal Antibody

The antibody against SFRP2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human SFRP2 (NP_003004.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-07941A

Number

Cat.No	ADA-07941A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SFRP2
Target Synonyms	FRP-2; SARP1; SDF-5; [KD Validated] SFRP2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa	Application	ELISA, WB, IF/ICC

Cat.No

ADA-07941A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SFRP2

Target Synonyms

FRP-2; SARP1; SDF-5; [KD Validated] SFRP2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa

Application

ELISA, WB, IF/ICC

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SFRP2 (NP_003004.1).	Target Species	Human
Immunogen Sequence	MLQGPGSLLLLFLASHCCLGSARGLFLFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFA	Uniprot ID	Q96HF1

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SFRP2 (NP_003004.1).

Target Species

Human

Immunogen Sequence

MLQGPGSLLLLFLASHCCLGSARGLFLFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFA

Uniprot ID

Q96HF1

Background Information

Uniprot Id

Q96HF1
Target Species

Human
Target Name

SFRP2
Target Full Name

Secreted frizzled-related protein 2
Target Function

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Target Subcellular Location

Secreted.
Target Protein Families

Secreted frizzled-related protein (sFRP) family
Target Tissue Specificity

Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
Target Research Area

Cancer
Target Synonyms

AI851596; Frizzled related protein 2; FRP 2; FRP-2; FRP2; MGC128911; MGC153618; MGC53344; SARP 1; SARP-1; SARP1; SDF 5; SDF5; Secreted apoptosis related protein 1; Secreted apoptosis-related protein 1; Secreted frizzled related protein 2; Secreted frizzled-related protein 2; sFRP 2; sFRP-2; SFRP2; Sfrp2 protein ; SFRP2_HUMAN
Target Background

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.

Rabbit anti-Human SFRP2 Polyclonal Antibody

Specifications

Immunogen Information

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