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The antibody against SLC25A20 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-301 of human SLC25A20 (NP_000378.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against SLC25A20 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-301 of human SLC25A20 (NP_000378.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-02812A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC25A20 |
| Target Synonyms | CAC; CACT; SLC25A20 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat heart, T-47D, U2OS | Application | ELISA, WB, IF/ICC |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 1-301 of human SLC25A20 (NP_000378.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O43772 | Immunogen Sequence |
Uniprot Id
O43772
Target Species
Human
Target Name
SLC25A20
Target Full Name
Mitochondrial carnitine/acylcarnitine carrier protein
Target Function
Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
Target Involvement
Carnitine-acylcarnitine translocase deficiency (CACTD)
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Target Protein Families
Mitochondrial carrier (TC 2.A.29) family
Target Research Area
Signal Transduction
Target Synonyms
SLC25A20; CAC; CACTMitochondrial carnitine/acylcarnitine carrier protein; Carnitine/acylcarnitine translocase; CAC; Solute carrier family 25 member 20
Target Background
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
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