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The antibody against SLC35A2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human SLC35A2 (NP_001027460.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.
The antibody against SLC35A2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human SLC35A2 (NP_001027460.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.
Immunofluorescence analysis of HeLa cells using SLC35A2 antibody. Blue: DAPI for nuclear staining.
| Cat.No | ADA-02613A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC35A2 |
| Target Synonyms | UGT; CDGX; UGAT; UGT1; UGT2; UGTL; CDG2M; UGALT; UDP-Gal-Tr; SLC35A2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human SLC35A2 (NP_001027460.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P78381 | Immunogen Sequence |
Uniprot Id
P78381
Target Species
Human
Target Name
SLC35A2
Target Full Name
UDP-galactose translocator
Target Function
Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
Target Involvement
Congenital disorder of glycosylation 2M (CDG2M)
Target Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
Target Protein Families
Nucleotide-sugar transporter family, SLC35A subfamily
Target Synonyms
SLC35A2; UGALT; UGT; UGTL; UDP-galactose translocator; Solute carrier family 35 member A2; UDP-galactose transporter; UDP-Gal-Tr; UGT
Target Background
This gene encodes a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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