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The antibody against SLC39A4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 23-327 of human SLC39A4 (NP_570901.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against SLC39A4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 23-327 of human SLC39A4 (NP_570901.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with SLC39A4 using SLC39A4 Rabbit pAb at 1:2000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
| Cat.No | ADA-04117A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC39A4 |
| Target Synonyms | AEZ; ZIP4; AWMS2; SLC39A4 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 23-327 of human SLC39A4 (NP_570901.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6P5W5 | Immunogen Sequence |
Uniprot Id
Q6P5W5
Target Species
Human
Target Name
SLC39A4
Target Full Name
Zinc transporter ZIP4
Target Function
Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability.
Target Involvement
Acrodermatitis enteropathica, zinc-deficiency type (AEZ)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note=Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
Target Protein Families
ZIP transporter (TC 2.A.5) family
Target Tissue Specificity
Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum.
Target Synonyms
SLC39A4; ZIP4; Zinc transporter ZIP4; Solute carrier family 39 member 4; Zrt- and Irt-like protein 4; ZIP-4
Target Background
This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for this gene.
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