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Rabbit anti-Human SLC6A8 Polyclonal Antibody

The antibody against SLC6A8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 539-635 of human SLC6A8 (NP_005620.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06922A

The antibody against SLC6A8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 539-635 of human SLC6A8 (NP_005620.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-06922A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC6A8
Target SynonymsCRT; CT1; CRT1; CRTR; CTR5; CCDS1; CRT-1; SLC6A8FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive Samples293T, Mouse brain, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 539-635 of human SLC6A8 (NP_005620.1).Target SpeciesHuman
Immunogen SequenceVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVMUniprot IDP48029
Background Information
  • Uniprot Id

    P48029

  • Target Species

    Human

  • Target Name

    SLC6A8

  • Target Full Name

    Sodium- and chloride-dependent creatine transporter 1

  • Target Function

    Required for the uptake of creatine in muscles and brain.

  • Target Involvement

    Cerebral creatine deficiency syndrome 1 (CCDS1)

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A8 subfamily

  • Target Tissue Specificity

    Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.

  • Target Synonyms

    SLC6A 8; SLC6A8; Creatine transporter 1; Creatine transporter SLC6A8; CRT; CRTR; CT 1; CT1; MGC87396; SC6A8_HUMAN; Slc6a8; Sodium and chloride-dependent creatine transporter 1; Sodium- and chloride-dependent creatine transporter 1; Solute carrier family 6 (neurotransmitter transporter, creatine), member 8.; Solute carrier family 6 member 8

  • Target Background

    The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

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