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Rabbit anti-Human SLC9A9 Polyclonal Antibody

The antibody against SLC9A9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human SLC9A9 (NP_775924.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01516A

The antibody against SLC9A9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human SLC9A9 (NP_775924.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01516A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC9A9
Target SynonymsNHE9; AUTS16; SLC9A9FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, NIH/3T3, A-549, SH-SY5Y, U-251MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human SLC9A9 (NP_775924.1).Target SpeciesHuman
Immunogen SequenceMERQSRVMSEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLILRYATAPTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQGNAILEKMTFDUniprot IDQ8IVB4
Background Information
  • Uniprot Id

    Q8IVB4

  • Target Species

    Human

  • Target Name

    SLC9A9

  • Target Full Name

    Sodium/hydrogen exchanger 9

  • Target Function

    May act in electroneutral exchange of protons for Na(+) across membranes. Involved in the effusion of Golgi luminal H(+) in exchange for cytosolic cations. Involved in organelle ion homeostasis by contributing to the maintenance of the unique acidic pH values of the Golgi and post-Golgi compartments in the cell.

  • Target Involvement

    Autism 16 (AUTS16)

  • Target Subcellular Location

    Late endosome membrane; Multi-pass membrane protein.

  • Target Protein Families

    Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family

  • Target Tissue Specificity

    Ubiquitously expressed in all tissues tested. Expressed at highest levels in heart and skeletal muscle, followed by placenta, kidney, and liver. Expressed in the brain, in the medulla and spinal cord.

  • Target Synonyms

    5730527A11Rik; 9930105B05; AI854429; FLJ35613; Na(+)/H(+) exchanger 9; Nbla00118; NHE 9; NHE-9; NHE9; Putative protein product of Nbla00118; SL9A9_HUMAN; Slc9a9; Sodium/hydrogen exchanger 9; Sodium/proton exchanger NHE9; Solute carrier family 9 (sodium/hydrogen exchanger) isoform 9; Solute carrier family 9 (sodium/hydrogen exchanger) member 9; Solute carrier family 9 member 9

  • Target Background

    This gene encodes a sodium/proton exchanger that is a member of the solute carrier 9 protein family. The encoded protein localizes the to the late recycling endosomes and may play an important role in maintaining cation homeostasis. Mutations in this gene are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder.

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